Follow the timeline to see how we are gradually transforming the idea of the Central European Advanced Therapy and Immunotherapy Centre into practice.
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10.12.2024
Regina Demlova, Director of the CREATIC Centre of Excellence and the National Research Infrastructure CZECRIN, has been elected as the new Head of the Network Committee at ECRIN-ERIC. The election took place during the Network Committee meeting at the Paris office. The committee plays a key role in representing scientific partners and advising the Assembly of Members and the Director General. Comprising senior delegates from ECRIN member and observer countries, it ensures a coordinated approach to advancing clinical research in Europe. This appointment reflects Regina’s leadership in clinical research and gene therapy development, aligning with ECRIN’s mission to foster cross-border collaboration and innovation. We extend our appreciation to Christian Ohmann for his contributions as the previous Head of the Network Committee and look forward to strengthening research infrastructures under Regina’s leadership.
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14.11.2024
The online video platform DVTV recently featured an interview with immunologist Lenka Zdražilová Dubská, whose research is also part of MUNI | CREATIC. The discussion covered the development of new treatments, major breakthroughs in cancer research, and the role of personalized cancer vaccines for paediatric patients. These vaccines, developed in our laboratories, aim to stimulate the patient’s immune system using dendritic cells derived from their own blood. While these cells do not attack the tumour directly, they play a crucial role in activating immune responses that target cancer cells. Personalized cancer vaccines are particularly important for paediatric patients with high-risk solid tumours, where conventional treatment options remain limited.
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4.–5.11.2024
The first Central European Conference for Advanced Therapy and Immunotherapy took place with the theme "Rare diseases need innovative therapies — innovative therapies need scientific discoveries." The event featured panel discussions addressing the challenges of bringing advanced therapy medicinal products (ATMPs) into broader clinical use, barriers in regulatory and market access, and expected advancements in the field. The program included two key sessions: "Bridging the Gap: How to Overcome Barriers in the Translation of ATMPs to Clinical Practice" and "Innovative Pathways in Rare Disease Treatment: From Clinical Trials to Accessible Therapies," with leading experts contributing insights. Organizing this unique conference marks a significant milestone for MUNI | CREATIC in fostering dialogue and collaboration in advanced therapies.
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18.10.2024
The Velvet Innovation Meetup, hosted at the SIMU Simulation Centre, brought together over 160 participants and visitors for an evening of innovation, networking, and presentations of ground-breaking projects. The event was opened by Vice Dean Tomáš Kašpárek and featured ten innovative initiatives. The winning project was Spicy Cells from the Faculty of Science at Masaryk University, while the CREATIC Centre of Excellence also gained attention with a presentation by Lenka Součková, who introduced our work in a unique format and reached the second place of this speech competition! Attendees had the opportunity to explore the state-of-the-art facilities at SIMU and see first-hand how technological advancements are shaping the future of medical education.
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16.10.2024
We took part in the CEITEC Core Facility Day, an event bringing together experts from the Life Sciences sector. The program featured lectures, guided tours of advanced research facilities, and networking opportunities. Regina Demlova introduced the CREATIC Centre of Excellence, emphasizing our expertise in GMP development and manufacturing, with a focus on cell and gene therapies such as cell vaccines and CAR T-cells. A key element of our Clinical Trials Centre is the CZECRIN Large Research Infrastructure, which supports early-phase clinical research in collaboration with university hospitals. We provide a wide range of services, including open access for non-profit and commercial collaborations in the technology sector.
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13.10.2024
The Centre of Excellence CREATIC, Faculty of Medicine, Masaryk University at the 3rd Teaming Club Conference in Serbia!
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07.10.2024
Research breakfast. Today you could enjoy breakfast with researchers Regina Demlova and Jaroslav Sterba. As part of the regular "Research Breakfast" series, moderated by Tomas Kasparek, they focused on several interesting topics. This morning's menu included discussions about CREATIC Umbrella – our offering for researchers, Precision Medicine – a new frontier in (cancer) treatments, innovative products developed and manufactured by CREATIC, and a strong connection to pediatric oncology. They also explored possible challenges involved in manufacturing advanced products in gene therapy and shared insights about the new manufacturing unit that is currently being reconstructed.
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20.09.2024
The Third Working Breakfast
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18.09.2024
CREATIC at the CCP Phenogenomics Conference 2024. This week, the prestigious CCP Phenogenomics Conference 2024 is taking place at the Institute of Molecular Genetics of the Czech Academy of Sciences in Prague. On the first afternoon, Associate Professor Regina Demlová from the Faculty of Medicine, Masaryk University, delivered an inspiring presentation on cell and gene therapies being developed as part of the Teaming HE project at the Centre of Excellence CREATIC.
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11.09.2024
The reconstruction of our controlled environment facilities has officially begun. On September 11, 2024, Pavilion C03 was handed over to the consortium of contractors (OHLA ŽS, EP Rožnov, IDPS), marking the start of a key development phase for the Centre of Excellence CREATIC at the Faculty of Medicine, Masaryk University.
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08/2024
Submission of the Research and Development Strategy.
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08/2024
The submission of the Human Potential Centred HR Strategy and Recruitment and Selection Rules. The goal of implementing the HR strategy is to create a motivating and sustainable work environment through well-established personnel processes and their continuous optimization.
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25.07.2024
Visit from Fraunhofer IZI CREATIC Centre of Excellence Lékařská fakulta Masarykovy univerzity and production facilities were visited by Project Manager Training Unit and GMP-Development Mirko Müller from Fraunhofer IZI.
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01.07.2024
The Research Group of Lenka Zdražilová Dubská is being established: Innovative ATMP for Rare Diseases – Faculty of Medicine.
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25.06.2024
The Second Working Breakfast
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14.05.2024
A strategic brainstorming session in the heart of the White Carpathians was dedicated to intense discussions that propel us forward. As a team of professionals and leaders, we shared ideas and crafted strategies that define our future path.
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29.02.2024
New Research teams established in the Organisational Structure.
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22.02.2024
Rare Disease Day, a seminar that brought together representatives from the fields of genetics, research, and the production of advanced therapy medicinal products, as well as patient organizations and patients themselves. A total of 12 presentations were delivered, and the event concluded with a workshop by the CREATIC center on the topic of clinical trials.
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11.-12.02.2024
Our Director Regina Demlová and research Director Dalibor Valík visited Polish colleagues in Warsaw at the Children's Memorial Health Institute and started collaboration in ATMP research. Read more about the visit in the article here.
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01.02.2024
We have received an investment project decision to grant a subsidy – rebuilding of the Centre of Excellence CREATIC officially started.
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31.01.2024
1st Steering Committee meeting and the ISAB nomination.
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09-10.01.2024
Together with our colleagues in the project we organized a research meeting in Leipzig at Fraunhofer IZI, where we got a lot of inspiration for our further work.
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01.01.2024
Centre of Excellence CREATIC was established on the Faculty of Medicine MU. Read more in the news.
Entry of the Statute and Organizational rules into force. New Research Programs established in the Organisational structure.
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11.12.2023
Approval of the CREATIC Statute by the Faculty of Medicine management.
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01.12.2023
New project CERTAINTY lead by Fraunhofer IZI started and the CREATIC team is involved. Read more about the project in the article here.
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06.11.2023
Approval of the Centre of Excellence CREATIC by the Masaryk University Academic Senate.
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24.10.2023
Approval process of the Centre of Excellence CREATIC establishment started - approval by the Masaryk University Faculty of Medicine Academic Senate.
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19-20.09.2023
Together with our project partners we spent an inspiring time in Brno during our Kick-off meeting. We discussed our first steps in the project and presented our vision and goals to key stakeholders during the Kick-off ceremony. Read more about the event here.
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01.09.2023
The CREATIC project started its activities.
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01-04/2023
We prepare research projects with leading European partners for funding from Horizon Europe. The projects are focused on ATMP issues and, if supported, will constitute the first research-oriented project activities of CREATIC.
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12/2022
Announcement of the evaluation of the Horizon Europe Teaming for Excellence project. The evaluators supported CREATIC's vision for €15 million funding. Together with national co-funding, CREATIC will receive approximately €35 million over the next 6 years.
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10/2022
Designing CREATIC research projects eligible for funding from European and national grants. Communication with partners in the CREATIC consortium, preparation of basic proposals for the calls in the Horizon Europe Health Cluster.
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09/2022
The amount secured as complementary funding was confirmed by the Ministry of Education, Youth and Sports
07. 09. 2022 CREATIC full proposal for the second stage of the evaluation was submitted.
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05-06/2022
Preparation of the proposal for national complementary funding (P JAC, 02_22_001 Teaming-CZ I). The CREATIC INVESTMENT project supports the establishment of the CREATIC centre through investment funds for the adaptation of infrastructure facilities and the purchase or upgrade of equipment.
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02/2022
Invitation to submit a full proposal for the second stage of the evaluation.
Start of work on the full CREATIC project proposal: work breakdown structure, definition of specific activities, detailed definition of partners' roles in establishing and operating the centre, online and on-site project consortium meetings.
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01-10/2021
Contact with advanced partners: Fraunhofer IZI, University of Leipzig, University of Copenhagen (on-line and on-site meetings)
Preparing proposal for first stage of Teaming for Excellence call (HORIZON-WIDERA-2022-ACCESS-01-01- two-stage)
5. 10. 2021 Central European Advanced Therapy and Immunology Centre (CREATIC) proposal was submitted.
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07-12/2020
Discussion on the vision of the Centre of Excellence within Masaryk University. Formation of the Masaryk University project team.
The primary objective is to support the development of the Advanced Cell Immunotherapy Unit (ACIU) focused on the research and development of cell-based Advanced Therapy Medicinal Products (ATMPs). ACIU is nationally recognized unit of excellence certified by State Institute for Drug Control for GMP manufacturing of small volume cell-based products for personalised medicine.
